#real-world-studies .section-heading{margin-bottom: 0;}
#real-world-studies .section-heading::before{top: 2px;}
#real-world-studies .section-heading::after{bottom: 2px;}
#real-world-studies #studies-accordion .cmp-accordion__header .cmp-accordion__button {padding: 24px 35px 40px; align-items: flex-start;}
#real-world-studies #studies-accordion .cmp-accordion__header .cmp-accordion__button.cmp-accordion__button--expanded {padding: 24px 35px 49px;}
#real-world-studies #studies-accordion-item-208b85a604 .cmp-accordion__header .cmp-accordion__button.cmp-accordion__button--expanded {padding: 24px 35px 65px;}
#real-world-studies #studies-accordion .cmp-accordion__header .cmp-accordion__button .cmp-accordion__icon::before {position:relative;left: 12px;top: 5px;}
#real-world-studies #studies-accordion .cmp-accordion__header .cmp-accordion__button.cmp-accordion__button--expanded .cmp-accordion__icon::before {position:relative;left: 9px;top: 15px;}
#real-world-studies #studies-accordion .acc-btn-text h3{margin: 0 0 20px;color: #333F48;font-size: 24px;}
#real-world-studies #studies-accordion .acc-btn-text p{font-size: 18px;line-height: 22px;font-weight: 400;color: #333F48;}
#real-world-studies #studies-accordion .cmp-accordion__item{margin: 48px 0;}
#real-world-studies #studies-accordion .acc-subsection-title{padding: 8px 20px 12px;}

#real-world-studies #studies-accordion .acc-subsection-txtblock ul > ul.sublist{
    padding-left:30px !important;
}
#real-world-studies #txt_asthma_exacerbation_graph .disclaimer-footnote{font-size:16px;}
a.see-study-link{
  color: #333F48;
    text-decoration:underline;
}
#egpa-home a.see-study-link{text-decoration:none;}
#StudyD-Junplink,
#oral-corticosteroid-utilization #study-design,#real-world-studies #from-oral-corticosteroid{
scroll-margin-top:50px;    
}
#real-world-studies #studies-accordion .acc-subsection-txtblock ul ul.sublist li::before {
    content: "";
    background-color: #881857;
    width: 6px !important;
        height: 2px !important;
    border-radius:0px;
    display: block;
    position: absolute;
    left: -10px;
    top: 11px;
}
#real-world-studies #studies-accordion .acc-subsection-txtblock ul li ul li {
    padding-left: 0px;
}
#real-world-studies .inner-spacing.sec-chart-simple.sec-exacerbation-related-healthcare .lh-120_mobile.mb-5px_mobile.padding-top-space{
    display: block;
    text-indent: -6px;
    margin-left: 0;
        font-size: 16px !important;
}
#real-world-studies #studies-accordion .acc-subsection-txtblock .spacing-li {
    margin-bottom: 16px !important;
}
#real-world-studies .inner-spacing.sec-chart-simple.sec-fasenra-impact figure{
    margin: 24px 0 16px !important;
}
#real-world-studies .inner-spacing.sec-chart-simple.sec-fasenra-impact .acc-subsection-txtblock{
    margin:0px 0px 24px 0px;
}
#real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-transitioned-to figure{
        margin: 24px 0 0;
}
#real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-transitioned-to .acc-subsection-txtblock{
        margin: 8px 0 24px;
}
#real-world-studies .inner-spacing.sec-chart-simple.sec-exacerbation-related-healthcare .padding-top-space {
    padding-top: 5px;
    line-height: 120%;
}

#real-world-studies #studies-accordion .special-padding {
    margin-bottom: 103px;
    padding-right: 40px !important; 
}

#real-world-studies #studies-accordion .sec-patient-flow .acc-columns{display: flex;align-items: flex-start;justify-content: center;gap: 42px;}
#real-world-studies #studies-accordion .sec-patient-flow .acc-columns > figure{flex: 1;}
#real-world-studies #studies-accordion .sec-patient-flow .acc-columns > figure img{max-width: 654px;}
#real-world-studies #studies-accordion .sec-patient-flow .acc-columns > .acc-subsection-txtblock{flex: 1;margin: unset;}
#real-world-studies #studies-accordion .sec-patient-flow .acc-columns > .acc-subsection-txtblock{flex: 1;margin: unset;}

#real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-switch-cohort .acc-subsection-txtblock.common-class-one p.lh-120_mobile.mb-5px_mobile,
#real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-switch-cohort .acc-subsection-txtblock.common-class-one p.lh-120_mobile,
#real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-long-term-followup .acc-subsection-txtblock.common-class-one p.lh-120_mobile.mb-5px_mobile,
#real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-long-term-followup .acc-subsection-txtblock.common-class-one p.lh-120_mobile,
#real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-blood-eosinophil .acc-subsection-txtblock.common-class-one p.lh-120_mobile,
#real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-blood-eosinophil .acc-subsection-txtblock.common-class-one p.lh-120_mobile.mb-5px_mobile{
 font-size:16px !important;
}
#real-world-studies #studies-accordion .inner-spacing{padding: 0 31px 24px;}
#real-world-studies #studies-accordion .inner-spacing-2{padding: 0 31px 0}
#real-world-studies #studies-accordion .inner-spacing.sec-chart-simple figure{margin: 24px 0;}
#real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-blood-eosinophil figure{margin: 36px 0; }

#real-world-studies #studies-accordion .sec-change-annual-exacerbation figure img{max-width: 453px;}
#real-world-studies #studies-accordion .sec-percentage-medicare figure img{max-width: 758px;}
#real-world-studies #studies-accordion .sec-exacerbation-related-healthcare figure img{max-width: 757px;}
#real-world-studies #studies-accordion .sec-impact-treatment figure img,
#real-world-studies #studies-accordion .sec-real-world-exacerbation figure img{max-width: 818px;}
#real-world-studies #studies-accordion .sec-zephyr2-study-design figure img,
#real-world-studies #studies-accordion .sec-zephyr1-study-design figure img{max-width: 932px;}
#real-world-studies #studies-accordion .sec-blood-eosinophil figure img,
#real-world-studies #studies-accordion .sec-switch-cohort figure img,
#real-world-studies #studies-accordion .sec-long-term-followup figure img,
#real-world-studies #studies-accordion .sec-zephyr1-patient-flow figure img{max-width: 654px;}
#real-world-studies #studies-accordion .sec-fasenra-impact figure img{max-width: 827px;}
#real-world-studies #studies-accordion .sec-two-year-period figure img{max-width: 978px;}
#real-world-studies #studies-accordion .sec-biologic-experienced figure img{max-width: 1000px;}
#studies-accordion .acc-subheading h2 {color: #333F48;margin: 46px 0 56px;}
#studies-accordion .acc-subsection-txtblock ul{padding-left: 10px !important;}
#studies-accordion .acc-subsection-txtblock ul li{text-indent: unset;padding-bottom: unset;position: relative;list-style: none;}
#studies-accordion .acc-subsection-txtblock ul li::marker{content: "";display: none;}
#studies-accordion .acc-subsection-txtblock ul li::before{
    content: "";
    background-color: #881857;
    width: 4px;
    height: 4px;
    border-radius: 10px;
    display: block;
    position: absolute;
    left: -10px;
    top: 10px;
}
#real-world-studies .pivotal-study-designs ul{padding-left: 23px !important;}
#real-world-studies .pivotal-study-designs ul li{color: #333F48;}
#real-world-studies .pivotal-study-designs ul li::marker{font-size: 10px;color: inherit;padding-left: 5px;}
#real-world-studies .pivotal-study-designs .btm-footnotes{font-weight: 400;font-family: 'myriad-pro';line-height: 120%;font-size: 14px;}


#real-world-studies #lgbg {
    padding-top: 60px;
}

span.no-wrap {
    white-space: nowrap;
}

#real-world-studies #studies-accordion>div:nth-child(2) {
    margin-top: 0;
}

#real-world-studies #studies-accordion .toggle-accordion>div {
    padding: 48px 0 24px;
}

#real-world-studies .toggle-accordion .collapse-all.active {
    display: flex;
    align-items: center;
    justify-content: flex-end;
}
/*
#real-world-studies .toggle-accordion .collapse-all.active::after {
    content: '-';
    font-size: 30px;
    display: inline-block;
    line-height: 0px;
    padding-bottom: 5px;
    padding-left: 4px;
}
*/
#real-world-studies .lfd-intro h1 {
    margin: 0 0 15px;
	font-family: "myriad-pro";
    font-weight: bold;
    font-size: 32px;
    line-height: 44.88px;    
}

.lfd-intro p {
    font-size: 18px;
}
#real-world-studies .lfd-intro p.bold-text-1{
    font-family: "myriad-pro";
    font-size: 18px;
    font-weight:700;
    margin-bottom:16px !important;
}
#real-world-studies .lfd-intro p.bold-text-2{
    font-family: "myriad-pro";
    font-size: 18px;
    font-weight:700;
}
#real-world-studies .lfd-intro p:not(:last-child) {
    margin-bottom: 20px;
}

#real-world-studies .text:has(.keep-reading-container) {
    width: 100%;
}

#real-world-studies .keep-reading-container {
    padding-bottom: 60px;
}

#real-world-studies .submit-request-container{
    display: flex;
    align-items: center;
    justify-content: center;
    width: 100%;
    gap: 32px;
}

#real-world-studies .submit-request-box {
    width: 400px;
    height: 200px;
    background-color: #FFFFFF;
    border-radius: 10px;
    box-shadow: 0px 2px 17px #0000001A;
    padding: 40px 30px;
    display: flex;
    flex-direction: column;
    align-items: center;
    justify-content: space-between;
}

#real-world-studies .submit-request-box p {
    color: #333F48;
    font-family: 'myriad-pro';
    font-weight: 700;
    font-size: 18px;
    line-height: 100%;
    text-align: center;
}

#real-world-studies .submit-request-button {
    background-color: #8C2064;
    border-radius: 10px;
    color: #FFFFFF;
    font-family: 'myriad-pro';
    font-weight: 700;
    font-size: 18px;
    line-height: 22px;
    min-height: 52px;
    width: 189px;
    display: flex;
    align-items: center;
    justify-content: center;
    gap: 16px;
    border: 2px solid #fff;
}

#real-world-studies .submit-request-button.learn-more-button {
    width: 162px;
}

#real-world-studies .submit-request-button::after {
    content: url('/content/dam/intelligentcontent/brands/fasenrastudies/us/en/images/global/right_arrow-white.svg');
    padding-top: 3px;
    line-height: 100%;
}

#real-world-studies .cmp-text {
    padding: 0;
}

.pivotal-study-designs h3, .pivotal-study-designs p {
    font-size: 18px;
}

#real-world-studies .pivotal-study-designs ul li {
    color: #333F48;
    font-family: 'myriad-pro';
    font-size: 18px;
    line-height: 22px;
    text-indent: 0;
    padding-bottom: 0px;
}

#real-world-studies #studies-accordion .sec-study-design figure img.desktop-only {
    margin: 32px 0;
    max-width: 932px;
}

#real-world-studies #studies-accordion .sec-study-design .acc-subsection-txtblock .subsection-txtblock-title{
    font-size: 18px;
    line-height: 25px;
}

#real-world-studies #studies-accordion .sec-study-design .acc-subsection-txtblock p.chart-disclaimer{
    margin-bottom: 13px;
}

#real-world-studies #studies-accordion .sec-change-annual-exacerbation .acc-subsection-txtblock{
    /*margin: 46px 0 24px;*/
    margin: 0px 0 24px;
}

#real-world-studies #studies-accordion .sec-change-annual-exacerbation .acc-subsection-txtblock p.disclaimer-footnote{
    margin-bottom: 37px;
}

#real-world-studies #studies-accordion .sec-annual-exacerbation .acc-subsection-txtblock {
    margin: 0 0 60px;
}

#real-world-studies #studies-accordion .sec-annual-exacerbation .acc-subsection-txtblock .chart-disclaimer{
    margin-bottom: 9px;
}

#real-world-studies #studies-accordion .sec-annual-exacerbation .acc-subsection-txtblock .disclaimer-footnote{
    margin-bottom: 67px;
}

#real-world-studies #studies-accordion .sec-respiratory-medication figure{margin: 24px 0 6px;}

#real-world-studies #studies-accordion .sec-respiratory-medication .acc-subsection-txtblock .disclaimer-footnote,
#real-world-studies .padding-top-space{
    margin-bottom: 102px;
}

#real-world-studies #studies-accordion .sec-impact-treatment .acc-subsection-txtblock .disclaimer-footnote {
    margin-bottom: 79px;
}

#real-world-studies #studies-accordion .inner-spacing.sec-exacerbation-related-healthcare figure,
#real-world-studies #studies-accordion .inner-spacing.sec-impact-treatment figure{
    margin: 32px 0 0px;
}

#real-world-studies #studies-accordion .sec-exacerbation-related-healthcare .acc-subsection-txtblock{
    margin: 7px 0 24px;
    margin-top: 9px;
}

#real-world-studies #studies-accordion .sec-impact-treatment .acc-subsection-txtblock{
    margin: 5px 0 24px;
}

#real-world-studies #studies-accordion .sec-impact-treatment .acc-subsection-txtblock p:nth-of-type(2){
    font-size: 18px;
    margin-bottom: 4px !important;
}

#real-world-studies #studies-accordion #text-44ce91dcf7 .acc-subheading.btm h2{
    margin-bottom: 3px;
}

#real-world-studies .inner-spacing.sec-zephyr2-study-design>.acc-subsection-title {
    margin-bottom: 48px;
}


#real-world-studies .inner-spacing.sec-chart-simple.sec-blood-eosinophil {
    padding-top: 60px;
}

#real-world-studies .inner-spacing.sec-chart-simple.sec-switch-cohort,
#real-world-studies .inner-spacing.sec-chart-simple.sec-long-term-followup {
    padding-top: 28px;
}

#real-world-studies #studies-accordion .inner-spacing.sec-zephyr1-study-design {
    padding-top: 19px;
    margin-bottom: 44px;
}

/*#real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-transitioned-to .disclaimer-footnote {
    max-width: 71% !important;
}*/

#real-world-studies #studies-accordion #txt_Impact_of_fasenra  .acc-subheading h2 {
    margin-top: 17px;
}

#real-world-studies .inner-spacing.sec-zephyr1-study-design .desktop-only {
    margin-bottom: 28px;
}

#real-world-studies #studies-accordion .inner-spacing.sec-zephyr1-patient-flow {
    padding-top: 97px;
    padding-bottom: 40px;
}

#real-world-studies #studies-accordion .inner-spacing.sec-respiratory-medication figure{
    margin: 32px 0 0;
}
#real-world-studies #studies-accordion .sec-respiratory-medication .acc-subsection-txtblock{
    margin: 5px 0;
}

/* References */
#real-world-studies .references{
    /*padding: 32px 72px; */
        padding: 32px 0px;
    max-width: 1296px;
    margin: 0 auto;
}

#real-world-studies .references p{
    /*padding: 32px 72px; */
    text-align: left;
    color: #333F48;
    font-family: 'myriad-pro';
    font-weight: 400;
    font-size: 18px;
    line-height: 22px;
}

#real-world-studies .references p b {
    font-weight: 700;
}

#studies-accordion .acc-subsection-txtblock p, #studies-accordion .acc-subsection-txtblock ul li {
    font-size: 18px;
}

#real-world-studies #studies-accordion .acc-subsection-txtblock p:not(:last-child){margin-bottom: unset;}

@media only screen and (min-width:992px){
    #real-world-studies #studies-accordion .inner-spacing.sec-switch-cohort { padding: 0 31px 50px;}
    #studies-accordion .acc-subsection-txtblock.first-block {margin: 24px 0 50px;}
    #real-world-studies #studies-accordion .inner-spacing.sec-real-world-exacerbation .acc-subsection-title+figure {margin-top: 45px;}
    #real-world-studies .inner-spacing.sec-chart-simple.sec-blood-eosinophil {
        margin-top: 80px;
    }
    
    #real-world-studies .mb-2_desktop {
        margin-bottom: 8px !important;  
    }
    #real-world-studies .mb-3_desktop {
        margin-bottom: 12px !important;  
    }
    #real-world-studies .mb-4_desktop {
        margin-bottom: 16px !important;  
    }
}    


@media only screen and (max-width:991px){
    #StudyD-Junplink,
    #oral-corticosteroid-utilization #study-design{
scroll-margin-top:0px;    
}
    #real-world-studies .inner-spacing.sec-change-annual-exacerbation.sec-chart-simple .acc-subsection-title h3{
           max-width: 90%;
          margin: 0 auto; 
    }
    #real-world-studies .inner-spacing.sec-chart-simple.sec-impact-treatment .acc-subsection-title h3{
          max-width: 90%;
          margin: 0 auto;  
    }
    #real-world-studies .inner-spacing.sec-chart-simple.sec-two-year-period .mobile-only {
        padding-bottom: 0px !important;
}
#real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-transitioned-to .acc-subsection-txtblock {
    margin: 8px 0 0px;
}
    #real-world-studies #studies-accordion .cmp-accordion__header .cmp-accordion__button,
    #real-world-studies #studies-accordion .cmp-accordion__header .cmp-accordion__button.cmp-accordion__button--expanded{padding: 26px 16px 25px;align-items: flex-start;}
    #real-world-studies #studies-accordion .inner-spacing{padding: 0 0px 24px;}

    #real-world-studies #studies-accordion .acc-subsection-txtblock,
    #real-world-studies #studies-accordion .sec-patient-flow .acc-columns{
        flex-direction:column;
        /* padding-left: 16px;
        padding-right: 16px; */
    }
    #real-world-studies #studies-accordion .sec-patient-flow .acc-columns {
        gap: 0;
    }

    #real-world-studies #studies-accordion .inner-spacing.sec-zephyr2-study-design .mobile-only {
        padding-bottom: 0;
    }

    #real-world-studies #studies-accordion-item-208b85a604 .inner-spacing.sec-zephyr2-study-design  {
        padding-bottom: 15px !important;
    }

    #real-world-studies #studies-accordion .inner-spacing.sec-zephyr2-study-design ul {
        padding-left: 11px !important;
    }
        #real-world-studies .inner-spacing.sec-chart-simple.sec-fasenra-impact .acc-subsection-txtblock {
        margin: 12px 16px 0px;
    }
    #real-world-studies #studies-accordion .sec-change-annual-exacerbation figure img{width: 279px;}

    #real-world-studies #lgbg {
        padding-top: 32px;
    }

    #real-world-studies #studies-accordion .inner-spacing-2 {
        padding: 0 16px 0;
    }

    #real-world-studies #studies-accordion p.special-padding.inner-spacing {
        font-size: 18px;
        padding: 0 17px 10px 16px !important;
    }

    #real-world-studies .keep-reading-container {
        width: auto;
    }

    #real-world-studies .submit-request-container{
        flex-direction: column;
    }

    #real-world-studies .submit-request-box {
        width: 350px;
    }

    #real-world-studies .keep-reading-container {
        padding-bottom: 32px;
    }

    #real-world-studies .references {
        padding: 32px 16px; 
        /*background-color: #F8F8F8;*/
    }

    #real-world-studies #studies-accordion .toggle-accordion div {
        padding: 32px 0 24px;
    }

    #real-world-studies .cmp-accordion__icon {
        padding-top: 8px;
    }

    #real-world-studies .cmp-accordion__button.cmp-accordion__button--expanded .cmp-accordion__icon {
        padding-top: 46px;
    }

    #real-world-studies .inner-spacing.sec-zephyr2-study-design>.acc-subsection-title {
        margin-bottom: 0;
    }

    #real-world-studies .inner-spacing.sec-chart-simple.sec-blood-eosinophil {
        padding-top: 0;
    }

    #real-world-studies .inner-spacing.sec-chart-simple.sec-switch-cohort,
    #real-world-studies .inner-spacing.sec-chart-simple.sec-long-term-followup {
        padding-top: 0;
    }
    #real-world-studies #studies-accordion .inner-spacing.sec-zephyr1-study-design {
        padding-top: 0;
    }
    #real-world-studies #studies-accordion .inner-spacing.sec-zephyr1-patient-flow {
        padding-top: 0;
        padding-bottom: 0;
    }

    #real-world-studies #studies-accordion .cmp-accordion__header .cmp-accordion__button, #real-world-studies #studies-accordion .cmp-accordion__header .cmp-accordion__button.cmp-accordion__button--expanded {
        /* padding-bottom: 16px !important; */
        padding-top: 32px;
    }

    #real-world-studies #studies-accordion .inner-spacing.sec-study-design,
    #real-world-studies #studies-accordion .inner-spacing.sec-change-annual-exacerbation.sec-chart-simple {
        padding-top: 16px;
    }
    #real-world-studies #studies-accordion .inner-spacing.sec-change-annual-exacerbation.sec-chart-simple,
    #real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-respiratory-medication,
    #real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-impact-treatment,
    #real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-transitioned-to,
    #real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-biologic-experienced {
        padding-bottom: 0 !important;
    }

    #real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-annual-exacerbation,
    #real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-exacerbation-related-healthcare  {
        padding-bottom: 16px !important;
    }
    #real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-exacerbation-related-healthcare {
        padding-bottom: 16px !important;
    }

    #real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-respiratory-medication .acc-subsection-title {
        margin-bottom: 0;
    }

    #real-world-studies #studies-accordion .inner-spacing.sec-patient-flow {
        padding-top: 40px;
    }

    #real-world-studies #studies-accordion .inner-spacing figure img {
        padding: 16px 0;
    }
    #real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-exacerbation-related-healthcare figure img {
    width: 294px
}
#real-world-studies #studies-accordion .inner-spacing.sec-impact-treatment figure img {

width: 294px;}
    #real-world-studies #studies-accordion .acc-subheading h2 {
        margin: 24px 0 16px;
    }

    #real-world-studies #studies-accordion .inner-spacing.sec-chart-simple figure {
        margin: 0;
    }
    #real-world-studies #studies-accordion #txt_Impact_of_fasenra .inner-spacing.sec-chart-simple figure,
    #real-world-studies #studies-accordion #txt_asthma_exacerbation_graph .inner-spacing.sec-chart-simple figure {
        margin: 0 16px;
        
    }
    
    #real-world-studies #studies-accordion .sec-zephyr2-study-design .acc-subsection-txtblock{
        margin-top: 20px;
    }

    #real-world-studies #studies-accordion .inner-spacing.sec-annual-exacerbation .acc-subsection-title{
        margin-bottom: 20px;
    }
    #real-world-studies #studies-accordion .inner-spacing.sec-annual-exacerbation figure img{
        padding: 0;
        margin-top: 0;
        padding-bottom: 16px;
                width: 294px;
    }
    #real-world-studies #studies-accordion .inner-spacing.sec-switch-cohort{
        padding: 0 0 50px;
    }
    
    #real-world-studies #studies-accordion .inner-spacing.sec-long-term-followup .acc-subsection-title{
        margin-bottom: 8px;
    }
    #real-world-studies #studies-accordion .inner-spacing.sec-zephyr2-study-design{
        padding: 0 0px 35px;
    }

    #real-world-studies #studies-accordion .inner-spacing.sec-blood-eosinophil .acc-subsection-title{
        margin-bottom: 7px;
    }    
}

/*New CSS*/

/* Text Indent Issue and font Size */
.acc-subsection-txtblock.common-class-one {
    text-indent: -5px;
  }
  .acc-subsection-txtblock.common-class-one p {
    font-size: 14px !important;
  }
  .extra-bottom-margin-ul{
    margin-bottom: 12px !important;
}

.extra-bottom-margin{
    margin: 0 0 2px !important;
}

#studies-accordion .acc-subsection-txtblock p.chart-disclaimer{
    margin-bottom: 16px;
}

#real-world-studies #studies-accordion .sec-exacerbation-related-healthcare .acc-subsection-txtblock {
    margin-top: 9px;
}
  /* Text Indent Issue and font Size */

#real-world-studies .li-texts {
    font-family: 'myriad-pro';
    font-weight: 400;
    font-size: 18px;
    line-height: 100%;
    margin-bottom: 15px;
}

#real-world-studies .more-space {
    padding-bottom: 10px;
}

#studies-accordion .acc-subheading.btm + p {
    font-size: 18px;
}

#studies-accordion .acc-subheading.btm h2 {
    font-size: 24px;
    line-height: 29px;
    font-weight: 700;
}

#real-world-studies #text-44ce91dcf7 > p {
    margin-bottom: 24px;
}

#real-world-studies .cost-text {
    padding-top: 30px;
    padding-bottom: 10px;
}

#real-world-studies .sea-home-title {
    font-family: 'myriad-pro';
    font-size: 32px;
    line-height: 29px;
    /*margin-top: 16px;*/
        margin-top: 32px;
    margin-bottom: 35px;
    color:#333F48;
    font-weight:700;
}
#real-world-studies #cont-body .cmp-text ul {
    padding-left: 17px !important;
}
#real-world-studies .content-center .lfd-intro .li-texts span{
        position: relative;
    left: -4px;
}
#real-world-studies .inner-spacing.sec-chart-simple.sec-impact-treatment .desktop-only {
    margin-top: 28px;
    margin-bottom: 5px;
}

#studies-accordion .acc-subsection-txtblock p.disclaimer-footnote {
    font-size: 18px;
}

#real-world-studies .inner-spacing.sec-chart-simple.sec-two-year-period .desktop-only {
    /*margin-bottom: 28px;*/
        margin-bottom: 0px;
}

#real-world-studies .inner-spacing.sec-chart-simple.sec-two-year-period .acc-subsection-txtblock {
    margin: 0 0 48px;
}

#real-world-studies .inner-spacing.sec-chart-simple.sec-transitioned-to p.disclaimer-footnote,
#real-world-studies .inner-spacing.sec-chart-simple.sec-biologic-experienced p.disclaimer-footnote {
    margin-bottom: 0px;
}

#real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-transitioned-to,
#real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-biologic-experienced {
    padding: 0 31px 4px;
}

#real-world-studies .padding-top-space {
    padding-top: 20px;
    font-family: 'myriad-pro';
    font-weight: 400;
    font-size: 14px !important;
    line-height: 115%;
    display: flex;
    flex-direction: row;
    margin-left: -5px;
}

  @media only screen and (max-width: 991px) {

    #real-world-studies .sea-home-title {
        /*font-size: 24px;*/
        line-height: 100%;
        margin-bottom: 20px;
    }

    #real-world-studies #studies-accordion .cmp-accordion__item{margin: 24px 0;} 

    #real-world-studies #studies-accordion .sec-annual-exacerbation .acc-subsection-txtblock {
        margin: 0 16px 60px;
    }

    #real-world-studies #studies-accordion .sec-patient-flow .acc-columns > .acc-subsection-txtblock,
    #real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-exacerbation-related-healthcare,
    #real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-impact-treatment .acc-subsection-txtblock,
    #real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-biologic-experienced figure,
    #real-world-studies .inner-spacing.sec-chart-simple.sec-two-year-period .acc-subsection-txtblock {
        margin-left: 16px;
        margin-right: 16px;
    }

    #real-world-studies #text-2ef17e7498 > p {
        margin-left: 16px;
        margin-right: 16px;
        max-width: 91% !important;
        min-width: 91% !important;
        font-size: 18px;
        margin-bottom: 30px;
    }

    #real-world-studies .inner-spacing.sec-chart-simple.sec-two-year-period .acc-subsection-txtblock.common-class-one {
        margin-left: 0;
        margin-right: 0;
        margin-top: 0 !important;
    }

    #real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-transitioned-to {
        padding-left: 0;
        padding-right: 0;
    }

    #real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-impact-treatment .acc-subsection-txtblock p.chart-disclaimer.mb-2_desktop {
        margin-bottom: 10px;
    }

    #real-world-studies .inner-spacing.sec-chart-simple.sec-two-year-period p.chart-disclaimer.mb-3_mobile.mb-2_desktop {
        margin-bottom: 8px !important;
    }

    #real-world-studies #studies-accordion .sec-impact-treatment .acc-subsection-txtblock p:nth-of-type(2) {
        line-height: 120%;
    }

    #real-world-studies #studies-accordion-item-208b85a604-panel {
        padding-bottom: 62px !important;
    }

    #real-world-studies #text-44ce91dcf7 > p {
        margin-bottom: 0;
        padding-bottom: 0 !important;
        padding-right: 0;
        margin-left: 16px;
        margin-right: 16px;
        max-width: 95% !important;
        min-width: 95% !important;
    }

    /*#real-world-studies .inner-spacing.sec-change-annual-exacerbation.sec-chart-simple .acc-subsection-title h3,
    #real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-annual-exacerbation .acc-subsection-title h3,
    #real-world-studies .inner-spacing.sec-chart-simple.sec-respiratory-medication .acc-subsection-title h3,
    #real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-exacerbation-related-healthcare .acc-subsection-title h3,
    #real-world-studies .inner-spacing.sec-chart-simple.sec-impact-treatment .acc-subsection-title h3,
    #real-world-studies .inner-spacing.sec-chart-simple.sec-blood-eosinophil .acc-subsection-title h3,
    #real-world-studies .inner-spacing.sec-chart-simple.sec-switch-cohort .acc-subsection-title h3,
    #real-world-studies .inner-spacing.sec-chart-simple.sec-long-term-followup .acc-subsection-title h3,
    #real-world-studies .inner-spacing.sec-chart-simple.sec-fasenra-impact .acc-subsection-title h3,
    #real-world-studies .inner-spacing.sec-chart-simple.sec-biologic-experienced .acc-subsection-title h3,
    #real-world-studies .inner-spacing.sec-chart-simple.sec-real-world-exacerbation .acc-subsection-title h3,
    #real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-transitioned-to .acc-subsection-title h3 {
        font-size: 16px;
        line-height: 22px;
        font-weight: 400;
    }*/
	#real-world-studies .inner-spacing.sec-chart-simple.sec-transitioned-to .acc-subsection-title h3{ padding-left: 2%; padding-right: 2%;}	
	#real-world-studies .inner-spacing.sec-chart-simple.sec-real-world-exacerbation .acc-subsection-title h3{ padding-left: 0; padding-right: 0;}
	#real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-exacerbation-related-healthcare div.acc-subsection-title h3{ padding-left: 1%; padding-right: 1%;}	
    #real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-transitioned-to .disclaimer-footnote {
        max-width: 100% !important;
    }

    #real-world-studies #studies-accordion-item-0f9fa2c85c-panel {
        padding-bottom: 70px;
    }

    #real-world-studies .inner-spacing.sec-chart-simple.sec-two-year-period .acc-subsection-txtblock {
        margin-bottom: 0;
    }

    #real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-biologic-experienced {
        padding: 0 0 4px;
    }

    #real-world-studies #studies-accordion #txt_Impact_of_fasenra .acc-subheading h2 {
        margin-top: 50px;
    }

    #real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-blood-eosinophil figure {
        margin-top: 0;
        margin-bottom: 0;
    }

    #real-world-studies .inner-spacing.sec-chart-simple.sec-exacerbation-related-healthcare .padding-top-space {
        margin-bottom: 50px !important;
    }

    #real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-exacerbation-related-healthcare .acc-subsection-title h3 {
        padding-left: 10%;
        padding-right: 10%;
    }
    
    /*#real-world-studies .inner-spacing.sec-chart-simple.sec-real-world-exacerbation .acc-subsection-title h3 {
        padding-left: 15%;
        padding-right: 15%;
    }*/

    #real-world-studies #studies-accordion .sec-annual-exacerbation .acc-subsection-txtblock .chart-disclaimer {
        margin-bottom: 15px;
    }

    #real-world-studies #studies-accordion .sec-change-annual-exacerbation .acc-subsection-txtblock p.disclaimer-footnote,
    #real-world-studies #studies-accordion .sec-respiratory-medication .acc-subsection-txtblock .disclaimer-footnote {
        margin-top: 15px;
    }

    #real-world-studies #studies-accordion .inner-spacing.sec-zephyr1-study-design .acc-subsection-txtblock ul {
        margin-top: 10px;
    }

    #real-world-studies #studies-accordion #text-44ce91dcf7 .acc-subheading.btm h2 {
        margin: 16px;
    }

    #studies-accordion .acc-subheading.btm + p {
        font-size: 16px;
    }

    #real-world-studies #studies-accordion .inner-spacing.sec-zephyr1-study-design {
        margin-bottom: 0;
        padding-bottom: 0;
    }

    #real-world-studies #studies-accordion #text-2ef17e7498 > div > h2 {
        margin-top: 20px;
        margin-left: 16px;
        margin-right: 16px;
    }

    #studies-accordion .inner-spacing.sec-study-design .acc-subsection-txtblock {
        margin-right: 4px;
    }

    #real-world-studies #studies-accordion .acc-subheading.btm.inner-spacing,
    #real-world-studies #studies-accordion .inner-spacing.sec-zephyr1-study-design figure .mobile-only {
        padding-bottom: 0;
    }

    #real-world-studies .li-texts {
        line-height: 120%;
        letter-spacing: -0.01em;
    }

    #real-world-studies #studies-accordion .special-padding {
        margin-bottom: 20px;
        padding-right: inherit !important;
    }
  
  /* reference */
  
  #real-world-studies .references p {
    padding: 2px 0px;
  }
  
  #real-world-studies .references {
    /*padding: 32px 32px;*/
   padding: 32px 16px;
  }
  
  /* reference */
  
  
  
  
  /* Spacing  */
  #real-world-studies .section-heading {
    margin-bottom: 16px;
  }
  
  #real-world-studies .lfd-intro p:not(:last-child) {
    margin-bottom: 16px;
  
  }
  #real-world-studies .lfd-intro h1 {
    margin: 0 0 7px;
  }

  #real-world-studies .li-texts:last-child {
    margin-bottom: 10px;
  }
  
  #real-world-studies #studies-accordion .acc-btn-text h3 {
    margin: 0 0 30px;
  }
  #real-world-studies #studies-accordion .inner-spacing.sec-study-design{
    padding-top: 6px;
    padding-bottom: 0px;
  }
  #real-world-studies #studies-accordion .sec-change-annual-exacerbation .acc-subsection-txtblock {
    /*margin: 0px 0 48px 16px;*/
    margin: 0px 0 48px 0px !important;
  }
  
  #real-world-studies #studies-accordion .sec-annual-exacerbation .acc-subsection-txtblock .disclaimer-footnote {
    margin-bottom: 64px;
  
  }
  #real-world-studies #studies-accordion .inner-spacing.sec-patient-flow {
    padding-top: 64px;
    padding-bottom: 24px;
  }
  #real-world-studies #studies-accordion .acc-subsection-title{
    margin-bottom: 10px;
  }
  #real-world-studies #studies-accordion .acc-subheading h2 {
    margin: 26px 0 16px;    
  }
  
  #studies-accordion .inner-spacing.sec-study-design figure {
    margin-top: 0px;
  }
  #studies-accordion .inner-spacing figure img {
    margin-bottom: 0px;
  }
  #real-world-studies #studies-accordion .inner-spacing.sec-annual-exacerbation .acc-subsection-title {
    margin-bottom: 24px;
  }
  #real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-annual-exacerbation{
    padding-bottom: 0px !important;
  }
  #real-world-studies #studies-accordion .sec-respiratory-medication .acc-subsection-txtblock {
    margin: 24px 16px 5px;
  }
  #real-world-studies #studies-accordion .sec-respiratory-medication .acc-subsection-txtblock .disclaimer-footnote, #real-world-studies .padding-top-space, #real-world-studies #studies-accordion .sec-impact-treatment .acc-subsection-txtblock .disclaimer-footnote {
    margin-bottom: 40px;
  }
  #real-world-studies #studies-accordion .sec-impact-treatment .acc-subsection-txtblock {
    margin: 32px 0 24px;
  }
  #real-world-studies #studies-accordion .acc-subheading h2 {
    margin: 40px 0 16px;
  }
  #real-world-studies #studies-accordion #text-44ce91dcf7 .acc-subheading.btm h2 {
    margin-bottom: 16px;
    margin-top: 16px;
  }
  #real-world-studies #studies-accordion .sec-zephyr2-study-design .acc-subsection-txtblock {
    margin-top: 0px;
  }
  #real-world-studies #studies-accordion .inner-spacing.sec-zephyr2-study-design {
    padding: 0 0px 32px;
  }
  #real-world-studies #studies-accordion .inner-spacing {
    padding: 0 0px 48px;
  }
    #real-world-studies #studies-accordion .sec-long-term-followup{
        padding: 0 0px 0px;
    }
  #real-world-studies #studies-accordion .sec-fasenra-impact{
      padding: 0 0px 32px;
  }
  #studies-accordion .acc-subsection-txtblock p.disclaimer-footnote {
    margin-bottom: 0px;
  }
  #real-world-studies #studies-accordion .sec-switch-cohort figure img{
    padding: 14px 16px 0;
  }
  #real-world-studies #studies-accordion .inner-spacing.sec-switch-cohort {
    padding: 0 0 48px;
  }
  #real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-impact-treatment .acc-subsection-title {
    padding: 8px 24px 12px;
  }
  
  #real-world-studies #studies-accordion .acc-subheading.btm + p {
    max-width: 100%;
  }
  
  #real-world-studies .cmp-accordion__icon {
    margin-left: -20px;  
  }
  
  #real-world-studies #studies-accordion .cmp-accordion__header .cmp-accordion__button .cmp-accordion__icon::before {
    position: relative;
    left: -8px;
    top: -3px;
  }
  
  #real-world-studies #studies-accordion .cmp-accordion__header .cmp-accordion__button.cmp-accordion__button--expanded .cmp-accordion__icon::before {
    position: relative;
    left: -4px;
    top: -4px;
  }
  
  #real-world-studies .mb-2_mobile {
    margin-bottom: 8px !important;  
  }
  #real-world-studies .mb-3_mobile {
    margin-bottom: 12px !important;  
  }
  #real-world-studies .mb-4_mobile {
    margin-bottom: 16px !important;  
  }
  
  #real-world-studies .lh-120_mobile {
    line-height: 120% !important;  
  }
  
  #real-world-studies .mb-5px_mobile {
    margin-bottom: 5px !important;  
  }
  
  #real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-blood-eosinophil img.mobile-only {
    padding: 16px 16px 0;
  }
  
  #real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-long-term-followup figure img {
    padding: 16px 16px 0;
  }
  
  #real-world-studies #studies-accordion #studies-accordion-item-0f9fa2c85c-button .acc-btn-text h3 {
    max-width: 296px;  
  }
  #real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-real-world-exacerbation .acc-subsection-title {
    padding: 8px 34px 12px;
  }
  
  #real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-real-world-exacerbation figure img,
  #real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-transitioned-to figure img{
    padding: 16px;
  }
  
  #real-world-studies .pivotal-study-designs .btm-footnotes {
    padding-right: 20px;  
  }

  #real-world-studies #studies-accordion-item-208b85a604-button > span.cmp-accordion__title > div > h3 {
    max-width: 80%;
  }
}

@media (min-width: 380px) and (max-width: 991px) {
    #real-world-studies #studies-accordion .acc-subheading.btm + p {
        min-width: 326px;
    }
    
    #real-world-studies #studies-accordion .acc-btn-text p {
        min-width: 326px;
    }
     #real-world-studies .cmp-accordion__item:nth-child(3) .cmp-accordion__button.cmp-accordion__button--expanded .cmp-accordion__icon,
     #real-world-studies .cmp-accordion__item:nth-child(4) .cmp-accordion__button.cmp-accordion__button--expanded .cmp-accordion__icon {
        padding-top: 20px;
    }
        #real-world-studies .cmp-accordion__icon {
        margin-left: -21px;
    }
        #real-world-studies #studies-accordion .cmp-accordion__header .cmp-accordion__button .cmp-accordion__icon::before {
        left: -6px ;
    }
        #real-world-studies #studies-accordion .acc-btn-text h3 {
            max-width:97%;
            }
        #real-world-studies .cmp-accordion__item:nth-child(3) .cmp-accordion__icon,
    #real-world-studies .cmp-accordion__item:nth-child(4) .cmp-accordion__icon{
        padding-top: 10px;
    }
}
  
  /*NEW CSS*/
  
  
  
  /*Feedback 14-08-25 */
  
  span.references-register-mark {
    font-size: 20px;
    position: relative;
    /*top: 3px;*/
    top: 1px;
  }
  
  #studies-accordion .acc-subsection-txtblock p.disclaimer-footnote {
    max-width: 100% !important;
  }
  
  #studies-accordion .acc-subsection-txtblock ul li ul li {
    padding-left: 16px;
  }
  
  #studies-accordion .acc-subsection-txtblock ul li ul li::before {
    border-radius: 0;
    width: 7px !important;
    height: 2.5px !important;
    top: 11px !important;
    left: 4px;
  }
  
@media (max-width: 991px) {
    #real-world-studies #cont-body .content-center .lfd-intro ul {
        padding-left: 18px !important;
    }
    #studies-accordion .acc-subsection-txtblock ul li ul li::before {
        top: 10px !important;
    }
    #real-world-studies #cont-body .cmp-text ul {
        padding-left: 13px !important;
    }

    #real-world-studies .li-texts:last-child {
        margin-bottom: 0;
    }
}




/* Compatibility - STARTS */

@media (min-width: 992px) and (max-width: 1439px) {
    
    #real-world-studies #lgbg {
        padding: 60px 0 0;
    }
    
    #real-world-studies #lgbg .content-center {
        padding: 0;
    }
    
    #real-world-studies .content-center {
        padding: 0;
    }
    
    #real-world-studies #studies-accordion .sec-study-design figure img.desktop-only,
    #real-world-studies #studies-accordion .sec-zephyr2-study-design figure img,
    #real-world-studies #studies-accordion .sec-two-year-period figure img,
    #real-world-studies #studies-accordion .sec-biologic-experienced figure img,
    #real-world-studies #studies-accordion .sec-real-world-exacerbation figure img,
    #real-world-studies #studies-accordion .sec-fasenra-impact figure img,
    #real-world-studies #studies-accordion .sec-impact-treatment figure img,
    #real-world-studies #studies-accordion .sec-zephyr1-study-design figure img {
        max-width: 780px;
    }
    
    #real-world-studies #studies-accordion .sec-patient-flow .acc-columns > figure img {
        max-width: 550px;
    }

    #real-world-studies #isinformation #isi-header,#real-world-studies #isinformation #isi {
        justify-content: flex-start;
    }

    #real-world-studies #isinformation .isi-container {
        width: 100%;
    }

    #real-world-studies #isinformation #isi-body {
        padding: 0;
    }

    #real-world-studies #isinformation #isi-body .isi-container {
        width: 100%;
    }

    #real-world-studies #isinformation #isi-body .isi-container .col:nth-of-type(1),
    #real-world-studies #isinformation #isi-body .isi-container .col:nth-of-type(2) {
        max-width: 50%;
    }
}



@media (min-width: 391px) and (max-width: 991px) {
    #real-world-studies #studies-accordion .inner-spacing figure img {
        width: 292px;
        margin: 0 auto;
    }
    
    #real-world-studies #studies-accordion .sec-patient-flow .acc-columns > figure {
        margin: 0 auto;
    }
    #real-world-studies #studies-accordion .acc-btn-text h3,
        #real-world-studies #studies-accordion #studies-accordion-item-0f9fa2c85c-button .acc-btn-text h3 {
        max-width:97%;
    }
    #real-world-studies #studies-accordion .cmp-accordion__header .cmp-accordion__button .cmp-accordion__icon::before {
        left: 5px;
    }
        #real-world-studies #studies-accordion .cmp-accordion__header .cmp-accordion__button.cmp-accordion__button--expanded .cmp-accordion__icon::before {
        left: 5px;
    }
}

@media (max-width: 389px) {
    #real-world-studies #studies-accordion .inner-spacing.sec-annual-exacerbation figure img,
        #real-world-studies #studies-accordion .inner-spacing.sec-chart-simple.sec-exacerbation-related-healthcare figure img,
        #real-world-studies #studies-accordion .inner-spacing.sec-impact-treatment figure img,
        #real-world-studies #studies-accordion .sec-change-annual-exacerbation figure img {
        width: 240px;
    }
    
    #real-world-studies .submit-request-box {
        width: 280px;
    }
    #real-world-studies #studies-accordion .cmp-accordion__header .cmp-accordion__button .cmp-accordion__icon::before {
        left: 10px !important;
    }
        #real-world-studies #studies-accordion .cmp-accordion__header .cmp-accordion__button.cmp-accordion__button--expanded .cmp-accordion__icon::before {
        left: 5px;
    }
}

/* Compatibility - ENDS */